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| HOW DOES CBD SKINCARE WORK? |
HOW DOES CBD SKINCARE WORK?
Our Endocannabinoid system is composed by 2 types of cannabinoid receptors, CB1 and CB2, and both are present in the skin, distributed through keratinocytes, melanocytes, in hair follicles and sebaceous and sweat glands. In simple terms, this means that the Cannabidiol that is applied to the skin can potentially connect with the receptors regulating certain skin physiological processes. However, although studies have demonstrated a range of effects for topical application, more conclusive clinical data is needed to confirm these results. The main functions attributed to CBD in skincare are as an antioxidant and anti-inflammatory.
The role of the Endocannabinoid system on immune regulation, supports its local therapeutic effects in the skin, as this system is involved in cutaneous function by regulating, among others; cell growth, differentiation and survival, immune and inflammatory responses. Therefore the disruption of the endocannabinoid system could be involved in skin diseases.
The mechanism of action for the benefits of CBD in topical usage has not yet fully been explained, but its hypothesis involves regulations on sebocyte proliferation, control of sebum production, anti-inflammatory and antiproliferative (inhibits cell growth) activity. Medical literature has shown some evidence of a role for CBD in the management of symptoms of skin conditions like psoriasis, eczema, pruritus, allergic contact dermatitis, atopic dermatitis and acne, by relieving chronic pain, modifying the itching sensation, and reducing inflammation.
Studies show that it may inhibit proliferation of epidermal keratinocytes and to stimulate apoptosis (cell death), cause a reduction of histamine responses in human skin, and there have been studies documenting its use in treating inflammatory acne vulgaris because of its ability to decrease proliferation of human sebocytes in vitro.
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